Title : An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors.

Pub. Date : 2009 Oct

PMID : 19500885






1 Functional Relationships(s)
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1 Substituted androstenedione derivatives with Delta(1), Delta(6) and Delta(1,6) unsaturations and 6-alkyl/6-phenyl aliphatic substitutions, are among the most potent steroid aromatase inhibitors known to date. Androstenedione cytochrome P450 family 19 subfamily A member 1 Homo sapiens