Title : Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution.

Pub. Date : 2009 Oct

PMID : 19497982






1 Functional Relationships(s)
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1 Nuclear accumulation of the active enzyme only correlated with histone H3K27 trimethylation among the epigenetic modifications evaluated, therefore pointing to the necessity of methionine adenosyltransferase I/III to guarantee the supply of S-adenosylmethionine for specific methylations. S-Adenosylmethionine methionine adenosyltransferase 1A Homo sapiens