Pub. Date : 2009 Jun
PMID : 19496669
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVE: To investigate cytochrome P450 (CYP) enzymes involved in metabolism of racemic and S-ketamine in various species and to evaluate metabolic interactions of other analgesics with ketamine. | Ketamine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
2 | OBJECTIVE: To investigate cytochrome P450 (CYP) enzymes involved in metabolism of racemic and S-ketamine in various species and to evaluate metabolic interactions of other analgesics with ketamine. | Ketamine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
3 | OBJECTIVE: To investigate cytochrome P450 (CYP) enzymes involved in metabolism of racemic and S-ketamine in various species and to evaluate metabolic interactions of other analgesics with ketamine. | Ketamine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
4 | OBJECTIVE: To investigate cytochrome P450 (CYP) enzymes involved in metabolism of racemic and S-ketamine in various species and to evaluate metabolic interactions of other analgesics with ketamine. | Ketamine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
5 | CONCLUSIONS AND CLINICAL RELEVANCE: Enzymes of the CYP 3A4 family and orthologs of CYP 2C9 were involved in ketamine metabolism in horses, dogs, and humans. | Ketamine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |