Title : Dissociation of efficacy and cytokine release mediated by an Fc-modified anti-CD3 mAb in a chronic experimental autoimmune encephalomyelitis model.

Pub. Date : 2009 Jul 25

PMID : 19477024






1 Functional Relationships(s)
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1 The combination of N297A dosing with cyclosporine A (CSA) pretreatment showed a significant decrease of TNFalpha, IL-6 and IP-10 without effect on clinical efficacy. Cyclosporine tumor necrosis factor Mus musculus