Title : ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells.

Pub. Date : 2009 May

PMID : 19476498






1 Functional Relationships(s)
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1 Taken together, our results provide evidence supporting the role of HSP70 in the protection of C2C12 cells from H(2)O(2)-induced and Smac-promoted apoptosis by preventing the release of Smac from mitochondria, thereby inhibiting activation of caspases-9 and -3. Hydrogen Peroxide heat shock protein 1B Mus musculus