Title : Pendrin as a regulator of ECF and blood pressure.

Pub. Date : 2009 Jul

PMID : 19474731






3 Functional Relationships(s)
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1 Recent evidence has demonstrated that an apical Cl-/HCO3- exchanger called pendrin is an absolute requirement for chloride reabsorption in the collecting system, indicating that chloride absorption is not passive and paracellular but is mediated by the intercalated cells. Chlorides solute carrier family 26, member 4 Mus musculus
2 Recent evidence has demonstrated that an apical Cl-/HCO3- exchanger called pendrin is an absolute requirement for chloride reabsorption in the collecting system, indicating that chloride absorption is not passive and paracellular but is mediated by the intercalated cells. Chlorides solute carrier family 26, member 4 Mus musculus
3 SUMMARY: Pendrin-mediated chloride transport through intercalated cells appears to be an independent and important determinant of renal NaCl handling and therefore might represent a new target for blood pressure control. Chlorides solute carrier family 26, member 4 Mus musculus