Title : The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways.

Pub. Date : 2009 Sep

PMID : 19467701






1 Functional Relationships(s)
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1 These results suggest that BisGMA released from composite resin may potentially affect the vitality of dental pulp and induce pulpal inflammation via stimulation of ROS production, MEK/ERK1/2 activation and subsequent COX-2 gene expression and PGE(2) production. Bisphenol A-Glycidyl Methacrylate mitogen-activated protein kinase 3 Homo sapiens