Title : Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation.

Pub. Date : 1991 Nov 15

PMID : 1946468






1 Functional Relationships(s)
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1 Here we show that the PMA-induced differentiation of SH-SY5Y cells grown in a serum-free medium is strongly potentiated by nanomolar concentrations of IGF-I, as judged by morphology and markers for neuronal differentiation--e.g., neuropeptide tyrosine and growth-associated protein 43. Tetradecanoylphorbol Acetate insulin like growth factor 1 Homo sapiens