Pub. Date : 2009 Aug 15
PMID : 19464362
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Myeloperoxidase interaction with peroxynitrite: chloride deficiency and heme depletion. | Chlorides | myeloperoxidase | Homo sapiens |
| 2 | Myeloperoxidase (MPO) is a hemoprotein involved in the leukocyte-mediated defense mechanism and uses hydrogen peroxide (H2O2) and chloride (Cl(-)) to produce hypochlorous acid. | Chlorides | myeloperoxidase | Homo sapiens |
| 3 | Myeloperoxidase (MPO) is a hemoprotein involved in the leukocyte-mediated defense mechanism and uses hydrogen peroxide (H2O2) and chloride (Cl(-)) to produce hypochlorous acid. | Chlorides | myeloperoxidase | Homo sapiens |
| 4 | Chloride binding to the active site of MPO constrains ONOO(-) binding by filling the space directly above the heme moiety or by causing a protein conformational change that constricts the distal heme pocket, thus preventing ONOO(-) from binding to MPO heme iron. | Chlorides | myeloperoxidase | Homo sapiens |
| 5 | Chloride binding to the active site of MPO constrains ONOO(-) binding by filling the space directly above the heme moiety or by causing a protein conformational change that constricts the distal heme pocket, thus preventing ONOO(-) from binding to MPO heme iron. | Chlorides | myeloperoxidase | Homo sapiens |