Title : Nicotinic acid-mediated activation of both membrane and nuclear receptors towards therapeutic glucocorticoid mimetics for treating multiple sclerosis.

Pub. Date : 2009

PMID : 19461950






1 Functional Relationships(s)
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1 By comparison, nicotinic acid provides even greater levels of NAD than nicotinamide in many tissues, while additionally activating the PPARgamma-dependent pathway already shown to provide relief in animal models of MS after activation of GPR109a/HM74a. Niacin peroxisome proliferator activated receptor gamma Homo sapiens