Title : Novel piperazine derivative PMS1339 exhibits tri-functional properties and cognitive improvement in mice.

Pub. Date : 2009 Nov

PMID : 19460190






3 Functional Relationships(s)
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1 Molecular docking studies using the X-ray crystal structure of AChE from Torpedo californica elucidated the interactions between PMS1339 and AChE: PMS1339 is well buried inside the active-site gorge of AChE interacting with Trp84 at the bottom, Tyr121 halfway down and Trp279 at the peripheral anionic site (PAS). Aminosalicylic Acid acetylcholinesterase Mus musculus
2 Molecular docking studies using the X-ray crystal structure of AChE from Torpedo californica elucidated the interactions between PMS1339 and AChE: PMS1339 is well buried inside the active-site gorge of AChE interacting with Trp84 at the bottom, Tyr121 halfway down and Trp279 at the peripheral anionic site (PAS). Aminosalicylic Acid acetylcholinesterase Mus musculus
3 Molecular docking studies using the X-ray crystal structure of AChE from Torpedo californica elucidated the interactions between PMS1339 and AChE: PMS1339 is well buried inside the active-site gorge of AChE interacting with Trp84 at the bottom, Tyr121 halfway down and Trp279 at the peripheral anionic site (PAS). Aminosalicylic Acid acetylcholinesterase Mus musculus