Title : Tumor markers and rectal cancer: support for an inflammation-related pathway.

Pub. Date : 2009 Oct 1

PMID : 19452524






2 Functional Relationships(s)
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1 Ibuprofen-type drugs, IL6 polymorphisms (rs1800796) and dietary alpha-tocopherol and lycopene significantly altered likelihood of having a TP53 mutation. Ibuprofen tumor protein p53 Homo sapiens
2 This was especially true for TP53 transversion mutations and dietary antioxidants (OR for beta-carotene 0.51 95% CI 0.27, 0.97, p trend 0.03; alpha-tocopherol 0.41 95% CI 0.20, 0.84, p trend 0.02) Beta-carotene and ibuprofen significantly altered risk of KRAS2 tumors. Ibuprofen tumor protein p53 Homo sapiens