Title : Alteration of TLR3 pathways by glucocorticoids may be responsible for immunosusceptibility of human corneal epithelial cells to viral infections.

Pub. Date : 2009 May 8

PMID : 19452017






2 Functional Relationships(s)
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1 The poly(I:C)-induced expressions of IL-6 and IL-8 were down-regulated by both DEX and CsA, while the expressions of IFN-beta and TLR3 were suppressed by DEX alone. Dexamethasone interferon beta 1 Homo sapiens
2 When HCECs were inoculated with HSV-1, DEX led to a decrease in the expression of IL6, IFN-beta, and TLR3, and an extension of plaque formation. Dexamethasone interferon beta 1 Homo sapiens