Title : A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells.

Pub. Date : 2009 Jul 16

PMID : 19448671






1 Functional Relationships(s)
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1 Thiol reactive cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ2), induced a novel, nonapoptotic and microtubule-associated protein 1 light chain 3 (MAP1 LC3) dependent but nonautophagic form of cell death in colon, breast and prostate cancer cell lines, characterized by extensive cytoplasmic vacuolation with dilatation of endoplasmic reticulum (ER). 15-deoxy-delta microtubule associated protein 1 light chain 3 alpha Homo sapiens