Title : Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.

Pub. Date : 2009 Jul

PMID : 19443904






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The hMYH R260Q mutant had severe defect in adenine DNA glycosylase activity, whereas hMYH H434D could excise adenines from A:8oxoG pairs but not from A:G mispairs. Adenine mutY DNA glycosylase Homo sapiens
2 The hMYH R260Q mutant had severe defect in adenine DNA glycosylase activity, whereas hMYH H434D could excise adenines from A:8oxoG pairs but not from A:G mispairs. Adenine mutY DNA glycosylase Homo sapiens