Title : Prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) synthesis is regulated by conjugated linoleic acids (CLA) in human macrophages.

Pub. Date : 2009 Mar

PMID : 19439810






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Prostaglandin E(2) and thromboxan A(2) which are a products of two izoformes of cyclooxygenases (COX-1 and COX-2) in macrophages, play an important role in this process. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Monocytes were differentiated to macrophages and cultured with 30 muM CLAs or linoleic acid for 48 h. The COX-1 and COX-2 products - PGE(2) and TXB(2), were measured by ELISA method. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens