Title : Morphine induces DNA damage and P53 activation in CD3+ T cells.

Pub. Date : 2009 Aug

PMID : 19397953






2 Functional Relationships(s)
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1 RESULTS: We show that p53 and damage-specific DNA binding protein 2 (ddb2) genes are up-regulated by morphine in a naloxone-sensitive manner. Naloxone tumor protein p53 Homo sapiens
2 Furthermore, the results indicate that DNA damage, quantified by apurinic-apyrimidinic site counting assay and phosphorylation of Ser-15 in P53 protein, is induced in CD3+ T cells by morphine in a naloxone-sensitive manner. Naloxone tumor protein p53 Homo sapiens