Pub. Date : 2009 Aug
PMID : 19397953
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GENERAL SIGNIFICANCE: Because it was shown that only the kappa opioid receptor gene is expressed in CD3+ T cells in the opioid receptor family, the present study suggests that morphine induces DNA damage through the action on the kappa opioid receptor, which leads to immune suppression by activation of P53-mediated signal transduction. | Morphine | opioid receptor kappa 1 | Homo sapiens |
| 2 | GENERAL SIGNIFICANCE: Because it was shown that only the kappa opioid receptor gene is expressed in CD3+ T cells in the opioid receptor family, the present study suggests that morphine induces DNA damage through the action on the kappa opioid receptor, which leads to immune suppression by activation of P53-mediated signal transduction. | Morphine | opioid receptor kappa 1 | Homo sapiens |