Title : Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. An assessment of the role of serines 1305/1306 and threonine 1348 by their replacement with neutral or negatively charged amino acids.

Pub. Date : 1991 Nov 15

PMID : 1939203






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. Threonine insulin Homo sapiens
2 Insulin promotes insulin receptor beta-subunit phosphorylation on tyrosine, serine, and threonine residues in a variety of cells, including simian COS cells which transiently express human insulin receptors following transfection with a cDNA encoding the wild-type receptor protein. Threonine insulin Homo sapiens
3 Following transient expression of each of these mutant receptors in COS cells, two-dimensional phosphopeptide mapping reveals that threonine 1348 is the major, if not the only, insulin-stimulated threonine phosphorylation site. Threonine insulin Homo sapiens
4 Following transient expression of each of these mutant receptors in COS cells, two-dimensional phosphopeptide mapping reveals that threonine 1348 is the major, if not the only, insulin-stimulated threonine phosphorylation site. Threonine insulin Homo sapiens