Title : The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes.

Pub. Date : 2009 Jun

PMID : 19389934






1 Functional Relationships(s)
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1 The resultant V600E(+)/p53(sh) melanocytes grew anchorage-independently in soft agar, formed pigmented lesions reminiscent of in situ melanoma in artificial skin reconstructs, and were weakly tumorigenic in vivo. Agar tumor protein p53 Homo sapiens