Pub. Date : 2009 Aug 1
PMID : 19389385
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study demonstrates that the anticoagulant activity of this oversulfated chondroitin sulfate is primarily dependent on heparin cofactor II mediated inhibition of thrombin. | Chondroitin Sulfates | coagulation factor II, thrombin | Homo sapiens |
| 2 | While oversulfated chondroitin sulfate binds tightly to antithrombin III, unlike heparin, OSCS does not induce antithrombin III to undergo the conformational change required for its inactivation of thrombin and factor Xa. | Chondroitin Sulfates | coagulation factor II, thrombin | Homo sapiens |