Title : Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis.

Pub. Date : 2009 Apr 23

PMID : 19389235






6 Functional Relationships(s)
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1 Recent evidence suggests that vitamin D may enhance the innate immune response by induction of cathelicidin (LL-37), an endogenous antimicrobial peptide produced by macrophages and neutrophils. Vitamin D cathelicidin antimicrobial peptide Homo sapiens
2 Thus, the relationship between vitamin D status and LL-37 production may be of importance for host immunity, but little data is available on this subject, especially in the setting of human sepsis syndrome and other critical illness. Vitamin D cathelicidin antimicrobial peptide Homo sapiens
3 It also establishes a positive association between vitamin D status and plasma LL-37, which suggests that systemic LL-37 levels may be regulated by vitamin D status. Vitamin D cathelicidin antimicrobial peptide Homo sapiens
4 It also establishes a positive association between vitamin D status and plasma LL-37, which suggests that systemic LL-37 levels may be regulated by vitamin D status. Vitamin D cathelicidin antimicrobial peptide Homo sapiens
5 It also establishes a positive association between vitamin D status and plasma LL-37, which suggests that systemic LL-37 levels may be regulated by vitamin D status. Vitamin D cathelicidin antimicrobial peptide Homo sapiens
6 It also establishes a positive association between vitamin D status and plasma LL-37, which suggests that systemic LL-37 levels may be regulated by vitamin D status. Vitamin D cathelicidin antimicrobial peptide Homo sapiens