Title : Smad2/3 is involved in growth inhibition of mouse embryonic palate mesenchymal cells induced by all-trans retinoic acid.

Pub. Date : 2009 Sep

PMID : 19388084






4 Functional Relationships(s)
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1 Smad2/3 is involved in growth inhibition of mouse embryonic palate mesenchymal cells induced by all-trans retinoic acid. Tretinoin SMAD family member 2 Mus musculus
2 The protein expression levels of p21, Smad2/3, phospho-Smad2, and phospho-Smad3 were increased, while phospho-Rb was decreased in MEPM after atRA treatment on GD 10. Tretinoin SMAD family member 2 Mus musculus
3 The protein expression levels of p21, Smad2/3, phospho-Smad2, and phospho-Smad3 were increased, while phospho-Rb was decreased in MEPM after atRA treatment on GD 10. Tretinoin SMAD family member 2 Mus musculus
4 Our study demonstrated that Smad2/3 regulation of p21 was partly required for atRA-induced cell cycle perturbations in MEPM cells. Tretinoin SMAD family member 2 Mus musculus