Pub. Date : 2009 May
PMID : 19387891
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lamotrigine (LTG), a diaminotriazine anti-epileptic, is principally metabolized at the 2-position of the triazine ring to form a quaternary ammonium glucuronide (LTGG) by uridine glucuronosyl transferease (UGT) 1A3 and UGT1A4. | ltgg | UDP glucuronosyltransferase family 1 member A3 | Homo sapiens |
| 2 | UGT1A4 and UGT1A3 catalysed the formation of LTGG with an intrinsic clearances of 0.28 and 0.02 microl min(-1) mg(-1) protein, respectively. | ltgg | UDP glucuronosyltransferase family 1 member A3 | Homo sapiens |