Title : CYP2B6 (c.516G-->T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients.

Pub. Date : 2009 Apr

PMID : 19371316






1 Functional Relationships(s)
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1 Multiple linear regression analysis indicated that the CYP2B6 c.516G-->T polymorphism and CYP2A6 slow-metabolizing variants accounted for as much as 36 and 12% of the total variance in efavirenz concentrations, respectively. efavirenz cytochrome P450 family 2 subfamily A member 6 Homo sapiens