Title : A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.

Pub. Date : 2009 Apr

PMID : 19356713






1 Functional Relationships(s)
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1 Insulin resistance induced by HF/BCAA feeding was accompanied by chronic phosphorylation of mTOR, JNK, and IRS1Ser307 and by accumulation of multiple acylcarnitines in muscle, and it was reversed by the mTOR inhibitor, rapamycin. Sirolimus insulin receptor substrate 1 Homo sapiens