Title : Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53.

Pub. Date : 2009 Jul 1

PMID : 19351655






1 Functional Relationships(s)
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1 We hypothesized that NRH:quinone oxidoreductase 2 (NQO2) is a candidate susceptibility gene for breast cancer because of its known enzymatic activity on estrogen-derived quinones and its ability to stabilize p53. Quinones tumor protein p53 Homo sapiens