Title : Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor.

Pub. Date : 2009 Jun

PMID : 19346435






2 Functional Relationships(s)
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1 We found that synthetic PPARgamma agonists, rosiglitazone (RGZ) and troglitazone (TGZ), induced proliferation of human bronchial epithelial cells, whereas the endogenous PPARgamma ligand, 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), inhibited cell growth. 15-deoxy-delta peroxisome proliferator activated receptor gamma Homo sapiens
2 We found that synthetic PPARgamma agonists, rosiglitazone (RGZ) and troglitazone (TGZ), induced proliferation of human bronchial epithelial cells, whereas the endogenous PPARgamma ligand, 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), inhibited cell growth. 15-deoxy-delta peroxisome proliferator activated receptor gamma Homo sapiens