Title : A DFT study of nucleobase dealkylation by the DNA repair enzyme AlkB.

Pub. Date : 2009 Apr 9

PMID : 19338370






1 Functional Relationships(s)
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1 Oxidative dealkylation is a unique mechanistic pathway found in the alpha-ketoglutarate-Fe(II)-dependent AlkB family of enzymes to remove the alkylation damage to DNA bases and regenerate nucleobases to their native state. ammonium ferrous sulfate alkB homolog 1, histone H2A dioxygenase Homo sapiens