Title : Chronic ouabain treatment exacerbates blood pressure elevation in spontaneously hypertensive rats: the role of vascular mechanisms.

Pub. Date : 2009 Jun

PMID : 19337130






1 Functional Relationships(s)
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1 This appears to involve a vascular mechanism, related to a reduced vasodilator influence of nitric oxide and endothelium-derived hyperpolarizing factor and increased production of vasoconstrictor prostanoids by COX-2. Prostaglandins prostaglandin-endoperoxide synthase 2 Rattus norvegicus