Title : Ceramide-induced autophagy: to junk or to protect cells?

Pub. Date : 2009 May

PMID : 19337026






2 Functional Relationships(s)
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1 Like amino acid starvation, ceramide triggers autophagy by interfering with the mTOR-signaling pathway, and by dissociating the Beclin 1:Bcl-2 complex in a c-Jun N-terminal kinase 1 (JNK1)-mediated Bcl-2 phosphorylation-dependent manner. Ceramides mitogen-activated protein kinase 8 Homo sapiens
2 Like amino acid starvation, ceramide triggers autophagy by interfering with the mTOR-signaling pathway, and by dissociating the Beclin 1:Bcl-2 complex in a c-Jun N-terminal kinase 1 (JNK1)-mediated Bcl-2 phosphorylation-dependent manner. Ceramides mitogen-activated protein kinase 8 Homo sapiens