Title : Fostamatinib, a Syk inhibitor prodrug for the treatment of inflammatory diseases.

Pub. Date : 2009 Mar

PMID : 19333898






1 Functional Relationships(s)
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1 Preclinical studies of R-406 or fostamatinib demonstrated a significant reduction in major inflammatory mediators such as TNFalpha, IL-1, IL-6 and IL-18, leading to reduced inflammation and bone degradation in models of RA. fostamatinib interleukin 6 Homo sapiens