Title : Generation and fate of enamines in the microsomal metabolism of cyclic tertiary amines.

Pub. Date : 1991 Sep 30

PMID : 1930182






1 Functional Relationships(s)
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1 In cases where iminium-enamine coupling is sterically prevented, the iminium in equilibrium with enamine species can be studied independently and are found to be more potent metabolism-dependent inactivators of cytochrome P-450 than are the corresponding parent amines. Amines cytochrome P450 family 4 subfamily F member 3 Homo sapiens