Title : Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms.

Pub. Date : 2009 Mar

PMID : 19298750






1 Functional Relationships(s)
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1 CONCLUSION: On a molecular level, hyperbaric oxygen therapy leads to activation of ion channels, inhibition of hypoxia inducible factor-1alpha, up-regulation of Bcl-2, inhibition of MMP-9, decreased cyclooxygenase-2 activity, decreased myeloperoxidase activity, up-regulation of superoxide dismutase and inhibition of Nogo-A (an endogenous growth-inhibitory factor). Oxygen myeloperoxidase Homo sapiens