Title : The c-Jun N-terminal kinase mediates the induction of oxidative stress and insulin resistance by palmitate and toll-like receptor 2 and 4 ligands in 3T3-L1 adipocytes.

Pub. Date : 2009 Jul

PMID : 19277946






1 Functional Relationships(s)
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1 The JNK inhibitor, SP600125, attenuated insulin resistance mediated by SFA and Tlr agonists, which corresponded with a diminished proinflammatory response and reduced ROS accumulation. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens