Title : Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide.

Pub. Date : 2009 May

PMID : 19259068






1 Functional Relationships(s)
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1 We have developed a peptide-like scaffold (regioselectively addressable functionalized template, RAFT), which holds four cyclo(-RGDfK-) (cRGD) motifs and proved that this molecule (called regioselectively addressable functionalized template-arginine-glycine-aspartic acid, RAFT-RGD) targets integrin alpha(v)beta(3) in vitro and in vivo. Arginine integrin subunit alpha V Homo sapiens