Title : Negative functional interaction of retinoic acid and TGF-beta signaling mediated by TG-interacting factor during chondrogenesis.

Pub. Date : 2009

PMID : 19255510






2 Functional Relationships(s)
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1 We found that atRA suppressed chondrogenesis and Smad2/3 phosphorylation regardless of the presence of TGF-beta3. Tretinoin SMAD family member 2 Mus musculus
2 Functional assays indicated that TGF-beta3 treatment or co-transfection of expressing Smad2/3 vectors suppressed atRA-induced RARE-tk-Luc activity. Tretinoin SMAD family member 2 Mus musculus