Pub. Date : 2009 Jun 19
PMID : 19254954
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor. | Tyrosine | glutathione S-transferase pi 1 | Homo sapiens |
| 2 | Here, we provide evidence that GSTP1 is a downstream EGFR target and that EGFR binds to and phosphorylates tyrosine residues in the GSTP1 protein in vitro and in vivo. | Tyrosine | glutathione S-transferase pi 1 | Homo sapiens |
| 3 | Mass spectrometry and mutagenesis analyses in a cell-free system and in gliomas cells identified Tyr-7 and Tyr-198 as major EGFR-specific phospho-acceptor residues in the GSTP1 protein. | Tyrosine | glutathione S-transferase pi 1 | Homo sapiens |
| 4 | Mass spectrometry and mutagenesis analyses in a cell-free system and in gliomas cells identified Tyr-7 and Tyr-198 as major EGFR-specific phospho-acceptor residues in the GSTP1 protein. | Tyrosine | glutathione S-transferase pi 1 | Homo sapiens |
| 5 | In human glioma and breast cancer cells, epidermal growth factor stimulation rapidly increased GSTP1 tyrosine phosphorylation and decreased cisplatin sensitivity. | Tyrosine | glutathione S-transferase pi 1 | Homo sapiens |