Title : Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.

Pub. Date : 2009 Feb 24

PMID : 19243225






1 Functional Relationships(s)
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1 These results support a prominent contribution of PIP2 depletion to the desensitization of TRPV1 and suggest the adaptation as a possible physiological function for the Ca(2+) influx through the channel. Phosphatidylinositol 4,5-Diphosphate transient receptor potential cation channel subfamily V member 1 Homo sapiens