Title : Huntingtin promotes cell survival by preventing Pak2 cleavage.

Pub. Date : 2009 Mar 15

PMID : 19240112






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When cells are exposed to Fas-related signals, the ubiquitously expressed p21-activated kinase 2 (Pak2) can be activated via cleavage by caspases to release a constitutively active C-terminal fragment, which mediates cell death. ammonium ferrous sulfate caspase 8 Homo sapiens