Title : Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish.

Pub. Date : 2009 Jun

PMID : 19233942






2 Functional Relationships(s)
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1 Knockdown of NRF2 increased mortality following tBOOH challenge, prevented significant upregulation of antioxidant genes following both tBOOH and BNF + ANF exposures, and exacerbated BNF + ANF-related deformities. tert-Butylhydroperoxide nfe2 like bZIP transcription factor 2a Danio rerio
2 Knockdown of NRF2 increased mortality following tBOOH challenge, prevented significant upregulation of antioxidant genes following both tBOOH and BNF + ANF exposures, and exacerbated BNF + ANF-related deformities. tert-Butylhydroperoxide nfe2 like bZIP transcription factor 2a Danio rerio