Title : Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteers.

Pub. Date : 2009 Jun

PMID : 19221727






2 Functional Relationships(s)
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1 The AUC of E-3174 decreased significantly with a silymarin pretreatment in both CYP2C9*1/*1 and the CYP2C9*1/*3 subjects. losartan carboxylic acid cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 The AUC of E-3174 decreased significantly with a silymarin pretreatment in both CYP2C9*1/*1 and the CYP2C9*1/*3 subjects. losartan carboxylic acid cytochrome P450 family 2 subfamily C member 9 Homo sapiens