Title : Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes.

Pub. Date : 2009 Mar 1

PMID : 19217790






1 Functional Relationships(s)
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Protein Name
Organism
1 DPP-4, a protease that specifically cleaves dipeptides from proteins and oligopeptides after a penultimate N-terminal proline or alanine, is involved in the degradation of a number of neuropeptides, peptide hormones and cytokines, including the incretins GLP-1 and GIP. Proline dipeptidyl peptidase 4 Homo sapiens