Pub. Date : 1990 Aug 1
PMID : 19215384
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Abstract In order to get better characterization of androgenic hormones on the functionality of the alpha(2)-adrenergic system and widen our previous studies, we investigated the effect of clonidine on the growth hormone (GH) secretion in male Wistar rats of various ages: 7-, 14- and 30-day old and adult, adult male castrated rats with and without testosterone treatment. | Clonidine | gonadotropin releasing hormone receptor | Rattus norvegicus |
| 2 | Abstract In order to get better characterization of androgenic hormones on the functionality of the alpha(2)-adrenergic system and widen our previous studies, we investigated the effect of clonidine on the growth hormone (GH) secretion in male Wistar rats of various ages: 7-, 14- and 30-day old and adult, adult male castrated rats with and without testosterone treatment. | Clonidine | gonadotropin releasing hormone receptor | Rattus norvegicus |
| 3 | Two different patterns of the GH response to clonidine have been observed in the control and testosterone-treated young animals: clonidine at the dose 15 mug/kg intraperitoneally had no effect on the GH secretion in 7- to 14-day old rat pups. | Clonidine | gonadotropin releasing hormone receptor | Rattus norvegicus |
| 4 | In 30-day old rats clonidine affected GH secretion and this influence was more pronounced in the testosterone-treated animals than in the controls. | Clonidine | gonadotropin releasing hormone receptor | Rattus norvegicus |
| 5 | The decrease in the circulating testosterone levels caused by castration in adult male rats caused a decreased GH response to clonidine. | Clonidine | gonadotropin releasing hormone receptor | Rattus norvegicus |