Title : Valproic acid induces transcriptional activation of human GD3 synthase (hST8Sia I) in SK-N-BE(2)-C human neuroblastoma cells.

Pub. Date : 2009 Jan 31

PMID : 19214441






4 Functional Relationships(s)
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1 Valproic acid induces transcriptional activation of human GD3 synthase (hST8Sia I) in SK-N-BE(2)-C human neuroblastoma cells. Valproic Acid ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Homo sapiens
2 In this study, we have shown the transcriptional regulation of the human GD3 synthase (hST8Sia I) induced by valproic acid (VPA) in human neuroblastoma SK-N-BE(2)-C cells. Valproic Acid ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Homo sapiens
3 In this study, we have shown the transcriptional regulation of the human GD3 synthase (hST8Sia I) induced by valproic acid (VPA) in human neuroblastoma SK-N-BE(2)-C cells. Valproic Acid ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Homo sapiens
4 Site-directed mutagenesis and electrophoretic mobility shift assay indicated that the NF-kappaB binding site at -731 to -722 was crucial for the VPA-induced expression of hST8Sia I in SK-N-BE(2)-C cells. Valproic Acid ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 Homo sapiens