Title : Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population.

Pub. Date : 2009 Mar

PMID : 19214144






1 Functional Relationships(s)
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1 None of these mutations had any effect on MRP1/ABCC1 expression and trafficking, but that Arg723Gln mutation significantly reduced MRP1/ABCC1-mediated resistance to daunorubicin, doxorubicin, etoposide, vinblastine, and vincristine. Etoposide ATP binding cassette subfamily C member 1 Homo sapiens