Pub. Date : 2009 Feb 10
PMID : 19187036
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Moreover, hRPA binds to a 26-mer purine-rich quadruplex-forming sequence with an affinity indistinguishable from that for binding to the complementary pyrimidine-rich sequence. | pyrimidine | replication protein A1 | Homo sapiens |
2 | Thus, DNA secondary structures can significantly modulate the binding affinity of hRPA over and above its known preference for pyrimidine-rich single-stranded sequences, so that at least some intramolecular G-quadruplex structures may not inhibit hRPA binding during DNA replication. | pyrimidine | replication protein A1 | Homo sapiens |