Title : Enhanced bioavailability of etoposide after oral or intravenous administration of etoposide with kaempferol in rats.

Pub. Date : 2009 Jan

PMID : 19183886






2 Functional Relationships(s)
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1 The enhanced bioavailability of oral etoposide by kaempferol could have been due to an inhibition of cytochrom P450 (CYP) 3A and P-glycoprotein (P-gp) in the intestinal or decreased total body clearance in the liver by kaempferol. Etoposide ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
2 The enhanced bioavailability of oral etoposide by kaempferol could have been due to an inhibition of cytochrom P450 (CYP) 3A and P-glycoprotein (P-gp) in the intestinal or decreased total body clearance in the liver by kaempferol. Etoposide ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus