Pub. Date : 2008 Dec
PMID : 19180880
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The effects of rapamycin on interleukin-1 beta (IL-1 beta)-induced mRNA and protein changes of low-density lipoprotein receptor (LDLR) and ATP-binding cassette transporter A1 (ABCA1) were assayed by quantitative real-time PCR and Western blot. | Sirolimus | ATP binding cassette subfamily A member 1 | Homo sapiens |
2 | The effects of rapamycin on interleukin-1 beta (IL-1 beta)-induced mRNA and protein changes of low-density lipoprotein receptor (LDLR) and ATP-binding cassette transporter A1 (ABCA1) were assayed by quantitative real-time PCR and Western blot. | Sirolimus | ATP binding cassette subfamily A member 1 | Homo sapiens |
3 | Rapamycin dose-dependently suppressed the increased expression of LDLR induced by IL-1 beta and up-regulated the suppressed expression of ABCA1 caused by IL-1 beta. | Sirolimus | ATP binding cassette subfamily A member 1 | Homo sapiens |