Title : Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells.

Pub. Date : 2009 Mar 1

PMID : 19171135






2 Functional Relationships(s)
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1 Endothelin-1-induced IL-6 production was markedly attenuated by EGTA and various Ca(2+) channel inhibitors such as 3,5-bis(trifluoromethyl)-1H-pyrazole derivative (BTP-2), 1-[beta-[3-(4-methoxyphenyl)propoxy]-4-methoxyphenethyl]-1H-imidazole hydrochloride (SKF96365), and nifedipine. Nifedipine endothelin 1 Homo sapiens
2 Endothelin-1-induced increases in intracellular Ca(2+) concentrations were significantly inhibited in Ca(2+)-free solution and by BTP-2, SKF96365, and nifedipine. Nifedipine endothelin 1 Homo sapiens